Polynucleotide treatment; otherwise known as salmon‑DNA skin resurfacing; is making waves as the latest frontier in non‑surgical skin care. At Medusa Beauty Zone, based in Shoreditch, London, the revolutionary treatment is administered with precision and bespoke care. Let's take a look at why polynucleotide treatment London has become the treatment to try, particularly for sensitive areas such as the delicate under eyes.
What Are Polynucleotides?
Developed from highly purified salmon sperm DNA (PDRN), polynucleotides are biocompatible molecules with the ability to function as strong cellular messengers. They activate fibroblast cell function, which increases the production of collagen and elastin; crucial in securing rejuvenated, youthful-looking skin.
They are regarded as being regenerative in action. Rather than merely filling or covering up skin issues such as fillers or Botox, they assist the body in healing itself internally; improving long-term skin texture and architecture.
Why Use Polynucleotides Under Eyes?
The under-eye skin is delicate and susceptible to dark circles, puffiness, and premature creasing. Polynucleotide injections provide a subtle yet powerful solution:
- Decrease fine lines and wrinkles
- Enhance circulation and moisture
- Thin out thinning under-eye skin
- Boost texture and tightness with low downtime
Due to its power to hydrate and rejuvenate, polynucleotide treatment is quickly becoming the go-to under-eye treatment for those who are not yet ready for tear trough filling or surgical blepharoplasty.
Treatment Process & "Before and After"
1. Consultation – Your practitioner assesses your skin type, talks through concerns, and creates a tailored protocol.
2. Treatment – A numbing cream is applied. Micro-needles or cannulas are used, and the polynucleotides are injected into areas as desired.
3. Recovery – Minimal redness or swelling should be noted immediately after treatment, but this typically resolves in 24–48 hours.
4. Results – Visible hydration and firmness are apparent after the initial session. Maximum results are usually achieved after 3–4 sessions, 2–4 weeks apart.
Patients frequently send polynucleotides before and after photos with excellent improvement in:
- Crepey texture near eyes
- Fine lines on cheeks and forehead
- Redness and dullness in skin tone
Ideal Application for Polynucleotide Injections
Although under-eye treatment is one of the most sought-after treatments, this treatment can also be applied to:
- General rejuvenation of face (forehead, cheeks, jawline)
- Smoothing wrinkles around mouth
- Enhancing tone on neck and décolleté
- Restoring elasticity to backs of hands
- Reviving skin after laser or microneedling treatments
- Helping with acne scarring and pigmentation problems
This makes it a versatile weapon of choice for a full-face regenerative treatment.
How Polynucleotides Compare to Other Treatments
| Treatment Type | Purpose | Duration of Results | Downtime |
| Polynucleotides | Regenerative hydration + firming | 6–9 months | Low (1–2 days) |
| Hyaluronic Acid Fillers | Volume restoration | 6–12 months | Moderate |
| Botox | Muscle relaxation | 3–4 months | Low |
| Profhilo | Hydration + firmness | 6 months | Low |
| PRP (Vampire Facial) | Skin rejuvenation | 4–6 months | Moderate |
Polynucleotide therapy bridges the gap between filler and biostimulation. It doesn’t change facial volume or muscle movement; it simply improves your skin quality from the inside out.
Safety & Suitability
Polynucleotide injections are safe for most skin types and tones. As they are derived from purified salmon DNA (not proteins), they are highly biocompatible and non-immunogenic. However, individuals with severe fish allergies should discuss this with their practitioner.
Common side effects include:
- Mild redness
- Light swelling
- Occasional bruising
These typically settle within 48 hours.
As a non-cross-linked product, it blends in perfectly with your skin without danger of lumpiness or unnatural texture.
Medusa Beauty Zone's Expertise
Medusa Beauty Zone introduces this international aesthetic trend to London with clinical excellence and personal service. Their Shoreditch clinic is renowned for:
- Specialised under-eye polynucleotide injections
- Combination protocols with microneedling or LED therapy
- Transparent pricing and expert follow-up
- Use of CE-approved and medically regulated products
Their staff of trained aesthetic professionals will make sure that your experience is both comfortable and effective.
Realistic Expectations & Timeline
| Week | Expected Change |
| 1 | Hydration boost and glow |
| 2–3 | Reduction in puffiness and fine lines |
| 4–6 | Improved skin density and firmness |
| 6–9 | Peak collagen stimulation |
| 12+ | Results maintain for several months |
Keep in mind, this is not a quick fix filler; it's a treatment that fortifies your skin from the inside out for naturally long-term advantages.
Frequently Asked Questions
Q1: How many sessions will I need?
Most patients need 3–4 sessions 2–4 weeks apart for best results.
Q2: Is there any downtime?
Minimal downtime. Mild swelling or bruising may be seen, but disappears rapidly.
Q3: Can I wear makeup after treatment?
Wait 24 hours after treatment before using makeup to minimize risk of irritation.
Q4: Who should avoid this treatment?
Individuals with pre-existing known allergies to fish or active cutaneous infection within the treatment field.
Q5: Is it possible to use this with Botox or fillers?
Yes. It works well with both and can improve overall quality of the skin without changing structure.
Why Polynucleotide Treatment is the Future of Aesthetics
What makes this therapy different is its cellular-level approach. Instead of temporarily masking flaws, it restructures the skin. The subtlety of the treatment is its superpower; it enhances your appearance in a way that friends may notice but won’t be able to pinpoint.
This “you but better” transformation is what modern aesthetics is all about.
Book Your Polynucleotide Consultation in London
If polynucleotide treatment London to get glowing under-eyes, silky smooth skin, and a radiant glow is on your radar, then Medusa Beauty Zone is where you begin.
Their expertly trained team paired with science-backed skincare technology guarantees you will experience an effective treatment in a soothing and nurturing atmosphere.
Location: Shoreditch, London
Call: +44 7900 878140
